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What is BiasAway?
The BiasAway software tool is introduced to generate nucleotide composition-matched DNA sequences. It is available as open source code from bitbucket.
The tool provides user with six approaches to generate synthetic or genomic background sequences matching mono- and dinucleotide composition of user-provided foreground sequences:
- synthetic k-mer shuffled sequences
- synthetic k-mer shuffled sequences in a sliding window
- genomic mononucleotide distribution matched sequences
- genomic mononucleotide distribution within a sliding window matched sequences